Urolithiasis – do ureaplasmas play a role in etiology.

Background and Objective: Urinary tract infections (UTIs) caused by urease-producing organisms, including ureaplasmas may contribute to the formation of urolithiasis. We aimed to determine the frequency of U. parvum and U. urealyticum among urology hospital patients with urinary stones. Methods: The study group included 30 men with urolithiasis. Urine samples were examined routinely for bacteria and by RT-PCR for ureaplasmal DNA.  Statistical analysis was done by chi-square and Fisher test ( p<0.05 was statistically significant). Results & Conclusion: In patients with urolithiasis DNAs of Ureaplasma spp. were detected 2 times more frequently (20%) compared with controls (10%). We suggest the necessity to include detection of Ureaplasma spp. in the group of patients with urolithiasis and sterile leukocyturia.